BDBM297394 US10112968, Compound C118
SMILES CN(CCCNC(=O)Nc1ccc(cc1)C(C)(C)C)C[C@H]1OC([C@H](O)[C@@H]1O)n1cnc2c(N)ncnc12
InChI Key InChIKey=DHTNDMXCZIAPMX-PSBUXNCMSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 1 hit for monomerid = 297394
TargetHistone-lysine N-methyltransferase, H3 lysine-79 specific(Homo sapiens (Human))
Epizyme
US Patent
Epizyme
US Patent
Affinity DataKi: 13nM Kd: 1.70nM Kon: 0.0200M-1s-1 Koff: 1.20E+7s-1Assay Description:Unless otherwise indicated, assays of DOT1L enzymatic activity were performed under balanced conditions (all substrates present at concentrations equ...More data for this Ligand-Target Pair