BDBM301791 N-[6-(2-Benzyloxy-ethoxy)-1H-indazol-3-yl]-(1-methyl-piperidin-4-ylamino)-benzamide::US9597317, 19

SMILES CN1CCC(CC1)Nc1ccccc1C(=O)Nc1n[nH]c2cc(OCCOCc3ccccc3)ccc12

InChI Key InChIKey=MARZBBLMAQLLHE-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 301791   

TargetMast/stem cell growth factor receptor Kit(Homo sapiens (Human))
Nerviano Medical Sciences

US Patent
LigandPNGBDBM301791(N-[6-(2-Benzyloxy-ethoxy)-1H-indazol-3-yl]-(1-meth...)
Affinity DataIC50:  61nMAssay Description:i. Enzyme The assay has been performed using KIT cytoplasmic domain product and purified in house as GST fused protein. The KIT protein (4.5 microM) ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetReceptor-type tyrosine-protein kinase FLT3(Homo sapiens (Human))
Nerviano Medical Sciences

US Patent
LigandPNGBDBM301791(N-[6-(2-Benzyloxy-ethoxy)-1H-indazol-3-yl]-(1-meth...)
Affinity DataIC50: <50nMAssay Description:i. Enzyme The assay was performed using FLT3 cytoplasmic domain product and purified in house as GST fused protein. The FLT3 protein (1 microM) was p...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent