BDBM304538 (R)-1-(3-chloro-4-(trifluoromethyl)benzyl)-4-(3-(methylsulfonyl)phenyl)-2-phenylpiperazine::US10144715, Compound 46-2

SMILES CS(=O)(=O)c1cccc(c1)N1CCN(Cc2ccc(c(Cl)c2)C(F)(F)F)[C@@H](C1)c1ccccc1

InChI Key InChIKey=SYWHAWSOSMSFBS-UHFFFAOYSA-N

Data  2 IC50  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 304538   

TargetOxysterols receptor LXR-beta(Human)
Vitae Pharmaceuticals

US Patent
LigandPNGBDBM304538((R)-1-(3-chloro-4-(trifluoromethyl)benzyl)-4-(3-(m...)
Affinity DataEC50:  1.05E+3nMAssay Description:This assay is based on the ability of the LXR-LBDs (LXRα and LXRβ) to recruit and interact with a co-activator peptide. This assay was run ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/30/2019
Entry Details
US Patent

TargetOxysterols receptor LXR-alpha(Human)
Vitae Pharmaceuticals

US Patent
LigandPNGBDBM304538((R)-1-(3-chloro-4-(trifluoromethyl)benzyl)-4-(3-(m...)
Affinity DataEC50:  3.94E+3nMAssay Description:This assay is based on the ability of the LXR-LBDs (LXRα and LXRβ) to recruit and interact with a co-activator peptide. This assay was run ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/30/2019
Entry Details
US Patent

TargetOxysterols receptor LXR-alpha(Human)
Vitae Pharmaceuticals

US Patent
LigandPNGBDBM304538((R)-1-(3-chloro-4-(trifluoromethyl)benzyl)-4-(3-(m...)
Affinity DataIC50: 5.00E+4nMAssay Description:This assay is based on the ability of the LXR-LBDs (LXRα and LXRβ) to recruit and interact with a co-activator peptide. This assay was run ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/30/2019
Entry Details
US Patent

TargetOxysterols receptor LXR-beta(Human)
Vitae Pharmaceuticals

US Patent
LigandPNGBDBM304538((R)-1-(3-chloro-4-(trifluoromethyl)benzyl)-4-(3-(m...)
Affinity DataIC50: 5.00E+4nMAssay Description:This assay is based on the ability of the LXR-LBDs (LXRα and LXRβ) to recruit and interact with a co-activator peptide. This assay was run ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/30/2019
Entry Details
US Patent