BDBM304654 (S)-(4-(3-isopropyl-4-((1-(2,2,2-trifluoroethyl)piperidin-4-yl)methyl)piperazin-1-yl)-2-(methylsulfonyl)phenyl)methanol::US10144715, Compound 48-50

SMILES CC(C)[C@H]1CN(CCN1CC1CCN(CC(F)(F)F)CC1)c1ccc(CCO)c(c1)S(C)(=O)=O

InChI Key InChIKey=ATFXXADQEVAPEW-UHFFFAOYSA-N

Data  2 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 304654   

TargetOxysterols receptor LXR-beta(Human)
Vitae Pharmaceuticals

US Patent
LigandPNGBDBM304654((S)-(4-(3-isopropyl-4-((1-(2,2,2-trifluoroethyl)pi...)
Affinity DataKi:  89nMAssay Description:Compounds of the invention were assessed in a competition binding assay where different concentrations of compounds were incubated with the LXR ligan...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/30/2019
Entry Details
US Patent

TargetOxysterols receptor LXR-alpha(Human)
Vitae Pharmaceuticals

US Patent
LigandPNGBDBM304654((S)-(4-(3-isopropyl-4-((1-(2,2,2-trifluoroethyl)pi...)
Affinity DataKi:  587nMAssay Description:Compounds of the invention were assessed in a competition binding assay where different concentrations of compounds were incubated with the LXR ligan...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/30/2019
Entry Details
US Patent