BDBM305887 US10144742, Compound I-49

SMILES O=C(NCCCn1ccnc1)c1ccc2nc(-c3cn[nH]c3)c(-c3ccccc3)nc2c1

InChI Key InChIKey=PECFZHVXHDUOIJ-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 305887   

TargetNicotinamide phosphoribosyltransferase(Human)
Millennium Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 305887BDBM305887(US10144742, Compound I-49)
Affinity DataIC50: 750nMAssay Description:To measure the inhibition of NAMPT activity hNAMPT protein stock and anti 6His-Tb (Cisbio; Cat. No. 61HISTLB) is diluted to 3× final concentration wi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/30/2019
Entry Details
US Patent