BDBM307615 2-(6-(4-cyclopropyl- 4H-1,2,4-triazol-3- yl)pyridin-2-yl)-5- (morpholine-4- carbonyl)isoindolin- 1-one::US10150755, Compound 7

SMILES: O=C(N1CCOCC1)c1ccc2C(=O)N(Cc2c1)c1cccc(n1)-c1nncn1C1CC1

InChI Key: InChIKey=KOULFMRALARHIM-UHFFFAOYSA-N

Data: 2 KI  3 IC50  1 Kd

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 307615   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Mitogen-activated protein kinase kinase kinase 5 (Human)	BDBM307615 (US10150755, Compound 7 | 2-(6-(4-cyclopropyl- 4H-1...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	<200	n/a	n/a	n/a	n/a	n/a	n/a
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Tumor necrosis factor (Human)	BDBM307615 (US10150755, Compound 7 | 2-(6-(4-cyclopropyl- 4H-1...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Myosin light chain kinase, smooth muscle (Human)	BDBM307615 (US10150755, Compound 7 | 2-(6-(4-cyclopropyl- 4H-1...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Tumor necrosis factor (Human)	BDBM307615 (US10150755, Compound 7 | 2-(6-(4-cyclopropyl- 4H-1...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	5.50E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase kinase kinase 5 (Human)	BDBM307615 (US10150755, Compound 7 | 2-(6-(4-cyclopropyl- 4H-1...) Show SMILES Show InChI	GoogleScholar	UniChem		<200	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Myosin light chain kinase, smooth muscle (Human)	BDBM307615 (US10150755, Compound 7 | 2-(6-(4-cyclopropyl- 4H-1...) Show SMILES Show InChI	GoogleScholar	UniChem		5.50E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair