BDBM31309 1,4-benzodiazepine-2,5-dione, 12f

SMILES C[C@H](N1[C@H](c2ccc(Cl)cc2)C(=O)N(CCN2CCOCC2)c2ccc(I)cc2C1=O)c1ccc(Cl)cc1N

InChI Key InChIKey=TXTIZPFXYRRDES-XRHLQHRESA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 31309   

TargetE3 ubiquitin-protein ligase Mdm2(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical

LigandPNGBDBM31309(1,4-benzodiazepine-2,5-dione, 12f)
Affinity DataIC50:  1.31E+4nMpH: 7.4 T: 2°CAssay Description:Test compound was incubated for 15 minutes with 30 nM peptide fluorescein-FMDYWEGLN (Fl 9mer) and 120 nM (glycine-HDM2 17-125) in assay buffer. The p...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed