BDBM31311 1,4-benzodiazepine-2,5-dione, 12h

SMILES COCCOCCN1c2ccc(I)cc2C(=O)N([C@@H](C)c2ccc(Cl)cc2)[C@H](c2ccc(Cl)cc2)C1=O

InChI Key InChIKey=MDTAPSOLFJDBQB-HFJWLAOPSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 31311   

TargetE3 ubiquitin-protein ligase Mdm2(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical

LigandPNGBDBM31311(1,4-benzodiazepine-2,5-dione, 12h)
Affinity DataIC50: >1.25E+4nMpH: 7.4 T: 2°CAssay Description:Test compound was incubated for 15 minutes with 30 nM peptide fluorescein-FMDYWEGLN (Fl 9mer) and 120 nM (glycine-HDM2 17-125) in assay buffer. The p...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed