BDBM313290 N-(6-methyl-5-(3- (oxetan-3- yl)phenyl)pyridin-2-yl)- 3-(trifluoromethyl)- benzamide::US10167279, Example 22::US10167279, Example 24

SMILES: Cc1ncc(NC(=O)c2cccc(c2)C(F)(F)F)cc1-c1cccc(c1)C1COC1

InChI Key: InChIKey=FXNXFVFPIIFJDM-UHFFFAOYSA-N

Data: 4 IC50

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Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 313290   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
RAF proto-oncogene serine/threonine-protein kinase (Human)	BDBM313290 (N-(6-methyl-5-(3- (oxetan-3- yl)phenyl)pyridin-2-y...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	595	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase B-raf [416-766,V600E] (Human)	BDBM313290 (N-(6-methyl-5-(3- (oxetan-3- yl)phenyl)pyridin-2-y...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	3.76E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
RAF proto-oncogene serine/threonine-protein kinase (Human)	BDBM313290 (N-(6-methyl-5-(3- (oxetan-3- yl)phenyl)pyridin-2-y...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	455	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase B-raf [416-766,V600E] (Human)	BDBM313290 (N-(6-methyl-5-(3- (oxetan-3- yl)phenyl)pyridin-2-y...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	3.52E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair