BindingDB PrimarySearch_ki

Search and Browse
- Target
- Compound
- Special tools
- Citation
- Special Data Sets
- Other Databases
  - PDB 85% 100% Seq ID
  - UniProtKB/Swiss-Prot
  - UniProtKB/TrEMBL
  - PubMed
Download
- All Compounds & Data
- Target Names &
  - Ki IC50 Kd EC50
  - ΔG° ΔH° -TΔS°
Enter Data

BDBM314688 US10513522, Example 1::US11214573, Example 1::US9611269, Example 1

SMILES: CC(C)NC(=O)c1ccc(cc1)N1CC(CC#N)(C1)n1cc(cn1)-c1ccnc2[nH]ccc12

InChI Key: InChIKey=WLQRZQUNUAGWJJ-UHFFFAOYSA-N

Data: 6 IC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 314688
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Tyrosine-protein kinase JAK1 (Human)	BDBM314688 (US9611269, Example 1 \| US10513522, Example 1 \| US1...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	<10	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
TBA					More data for this Ligand-Target Pair
Tyrosine-protein kinase JAK2 (Human)	BDBM314688 (US9611269, Example 1 \| US10513522, Example 1 \| US1...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	25	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
TBA					More data for this Ligand-Target Pair
Tyrosine-protein kinase JAK1 (Human)	BDBM314688 (US9611269, Example 1 \| US10513522, Example 1 \| US1...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	<10	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
TBA					More data for this Ligand-Target Pair
Tyrosine-protein kinase JAK2 (Human)	BDBM314688 (US9611269, Example 1 \| US10513522, Example 1 \| US1...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	25	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
TBA					More data for this Ligand-Target Pair
Tyrosine-protein kinase JAK1 [837-1142] (Human)	BDBM314688 (US9611269, Example 1 \| US10513522, Example 1 \| US1...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	<10	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
TBA					More data for this Ligand-Target Pair
Tyrosine-protein kinase JAK2 [828-1132] (Human)	BDBM314688 (US9611269, Example 1 \| US10513522, Example 1 \| US1...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	25	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
TBA					More data for this Ligand-Target Pair