BDBM315620 US10172859, Example 46::US11065253, Example 46::US9732094, Example 46::[2-Chloro-4-fluoro-5-(7- morpholin-4-yl- quinazolin-4-yl)phenyl]- (5-methylpyridazin-3- yl)methanol1H NMR (500 MHz, DMSO-d6) ppm = 9.11 (s, 1H), 9.00 (d, J = 2.0, 1H), 7.87 (d, J = 7.7, 1H), 7.67 (d, J = 9.5, 1H), 7.63-7.61 (m, 1H), 7.58 (dd, J = 9.4, 3.3, 1H), 7.53 (dd, J = 9.5, 2.5, 1H), 7.21 (d, J = 2.4, 1H), 6.65 (d, J = 4.9, 1H), 6.28 (d, J = 4.9, 1H), 3.80- 3.75 (m, 4H), 3.48-3.42 (m, 4H), 2.32 (s, 3H)

SMILES: Cc1cnnc(c1)C(O)c1cc(c(F)cc1Cl)-c1ncnc2cc(ccc12)N1CCOCC1

InChI Key: InChIKey=IWIZEUGGMFCIBN-UHFFFAOYSA-N

Data: 2 KI  3 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 315620   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
DNA-dependent protein kinase catalytic subunit (Human)	BDBM315620 (US10172859, Example 46 | [2-Chloro-4-fluoro-5-(7- ...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	18.5	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
DNA-dependent protein kinase catalytic subunit (Human)	BDBM315620 (US10172859, Example 46 | [2-Chloro-4-fluoro-5-(7- ...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	19	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
DNA-dependent protein kinase catalytic subunit (Human)	BDBM315620 (US10172859, Example 46 | [2-Chloro-4-fluoro-5-(7- ...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	18.5	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Potassium voltage-gated channel subfamily H member 2 (Human)	BDBM315620 (US10172859, Example 46 | [2-Chloro-4-fluoro-5-(7- ...) Show SMILES Show InChI	GoogleScholar	UniChem		2.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Potassium voltage-gated channel subfamily H member 2 (Human)	BDBM315620 (US10172859, Example 46 | [2-Chloro-4-fluoro-5-(7- ...) Show SMILES Show InChI	GoogleScholar	UniChem		2.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair