BDBM316983 N-[3-(4-Chloro-7H- pyrrolo[2,3-d]pyrimidine-5- carbonyl)-2,4-difluoro- phenyl]-5-propyl- benzenesulfonamide::US9617267, Compound P-1034

SMILES: CCCc1ccc(cc1)S(=O)(=O)Nc1ccc(F)c(C(=O)c2c[nH]c3ncnc(Cl)c23)c1F

InChI Key: InChIKey=WLPFZVLMFBVNJD-UHFFFAOYSA-N

Data: 8 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 316983   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Serine/threonine-protein kinase B-raf (Human)	BDBM316983 (US9617267, Compound P-1034 | N-[3-(4-Chloro-7H- py...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>100	n/a	n/a	n/a	n/a	n/a	n/a
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Epidermal growth factor receptor [T790M,L858R] (Human)	BDBM316983 (US9617267, Compound P-1034 | N-[3-(4-Chloro-7H- py...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>100	n/a	n/a	n/a	n/a	n/a	n/a
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RAF proto-oncogene serine/threonine-protein kinase (Human)	BDBM316983 (US9617267, Compound P-1034 | N-[3-(4-Chloro-7H- py...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	<100	n/a	n/a	n/a	n/a	n/a	n/a
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Cytochrome P450 1A2 (Human)	BDBM316983 (US9617267, Compound P-1034 | N-[3-(4-Chloro-7H- py...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Cytochrome P450 2C19 (Human)	BDBM316983 (US9617267, Compound P-1034 | N-[3-(4-Chloro-7H- py...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	7.50E+3	n/a	n/a	n/a	n/a	n/a	n/a
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Cytochrome P450 2C9 (Human)	BDBM316983 (US9617267, Compound P-1034 | N-[3-(4-Chloro-7H- py...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Cytochrome P450 2D6 (Human)	BDBM316983 (US9617267, Compound P-1034 | N-[3-(4-Chloro-7H- py...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Cytochrome P450 3A4 (Human)	BDBM316983 (US9617267, Compound P-1034 | N-[3-(4-Chloro-7H- py...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	7.50E+3	n/a	n/a	n/a	n/a	n/a	n/a
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