BDBM318025 US9624218, Example 19::US9624218, Example 34

SMILES CN1CCCc2c1nc([nH]c2=O)N1CCN(Cc2ccccn2)CC1

InChI Key InChIKey=DBBRJAYFAWANIO-UHFFFAOYSA-N

Data  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 318025   

TargetPoly [ADP-ribose] polymerase tankyrase-1(Homo sapiens (Human))
Eli Lilly

US Patent
LigandPNGBDBM318025(US9624218, Example 19 | US9624218, Example 34)
Affinity DataIC50:  19.9nMAssay Description:The enzymatic activity of hTNKS1 and hTNKS2 is assessed using an enzyme-linked immunosorbent assay (ELISA) which detects poly ADP ribose incorporated...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetPoly [ADP-ribose] polymerase tankyrase-2(Homo sapiens (Human))
Eli Lilly

US Patent
LigandPNGBDBM318025(US9624218, Example 19 | US9624218, Example 34)
Affinity DataIC50:  11.8nMAssay Description:The enzymatic activity of hTNKS1 and hTNKS2 is assessed using an enzyme-linked immunosorbent assay (ELISA) which detects poly ADP ribose incorporated...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetPoly [ADP-ribose] polymerase 1(Homo sapiens (Human))
Eli Lilly

US Patent
LigandPNGBDBM318025(US9624218, Example 19 | US9624218, Example 34)
Affinity DataIC50:  1.62E+4nMAssay Description:The Poly ADP-ribose polymerase 1(PARP1) assay is an ELISA which detects poly ADP ribose incorporated into plate-bound histone protein in a 384-well f...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetPoly [ADP-ribose] polymerase tankyrase-2(Homo sapiens (Human))
Eli Lilly

US Patent
LigandPNGBDBM318025(US9624218, Example 19 | US9624218, Example 34)
Affinity DataIC50:  11.6nMAssay Description:The enzymatic activity of hTNKS1 and hTNKS2 is assessed using an enzyme-linked immunosorbent assay (ELISA) which detects poly ADP ribose incorporated...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetPoly [ADP-ribose] polymerase 1(Homo sapiens (Human))
Eli Lilly

US Patent
LigandPNGBDBM318025(US9624218, Example 19 | US9624218, Example 34)
Affinity DataIC50:  5.39E+3nMAssay Description:The Poly ADP-ribose polymerase 1(PARP1) assay is an ELISA which detects poly ADP ribose incorporated into plate-bound histone protein in a 384-well f...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetPoly [ADP-ribose] polymerase tankyrase-1(Homo sapiens (Human))
Eli Lilly

US Patent
LigandPNGBDBM318025(US9624218, Example 19 | US9624218, Example 34)
Affinity DataIC50:  47.6nMAssay Description:The enzymatic activity of hTNKS1 and hTNKS2 is assessed using an enzyme-linked immunosorbent assay (ELISA) which detects poly ADP ribose incorporated...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent