BDBM31826 4-aminoquinazoline, 2a::BMC163482 Compound 3::CHEMBL188762

SMILES: CCC(=O)Nc1ccc2c(c1)c(ncn2)Nc3cccc(c3)Br

InChI Key: InChIKey=WUPUZEMRHDROEO-UHFFFAOYSA-N

Data: 8 IC50  1 Other

PDB links: 2 PDB IDs match this monomer.

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 9 hits for monomerid = 31826   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Proto-oncogene tyrosine-protein kinase Src (Chicken)	BDBM31826 (CHEMBL188762 | BMC163482 Compound 3 | 4-aminoquina...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	6.40E+3	n/a	n/a	n/a	n/a	7.0	23
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Proto-oncogene tyrosine-protein kinase Src [251-533,T338M] (Chicken)	BDBM31826 (CHEMBL188762 | BMC163482 Compound 3 | 4-aminoquina...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	n/a	n/a	n/a	7.0	23
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Epidermal growth factor receptor [668-1210] (Human)	BDBM31826 (CHEMBL188762 | BMC163482 Compound 3 | 4-aminoquina...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	0.430	n/a	n/a	n/a	n/a	7.5	23
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Epidermal growth factor receptor [696-1210,T790M] (Human)	BDBM31826 (CHEMBL188762 | BMC163482 Compound 3 | 4-aminoquina...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	360	n/a	n/a	n/a	n/a	7.5	23
TBA									Citation and Details
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Proto-oncogene tyrosine-protein kinase Src [251-533,S345C] (Chicken)	BDBM31826 (CHEMBL188762 | BMC163482 Compound 3 | 4-aminoquina...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	6.40E+3	n/a	n/a	n/a	n/a	7.5	23
TBA									Citation and Details
					More data for this Ligand-Target Pair
Proto-oncogene tyrosine-protein kinase Src [251-533,T338M,S345C] (Chicken)	BDBM31826 (CHEMBL188762 | BMC163482 Compound 3 | 4-aminoquina...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>5.00E+4	n/a	n/a	n/a	n/a	7.5	23
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Ephrin type-B receptor 2 (Human)	BDBM31826 (CHEMBL188762 | BMC163482 Compound 3 | 4-aminoquina...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.80E+5	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
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Epidermal growth factor receptor (Human)	BDBM31826 (CHEMBL188762 | BMC163482 Compound 3 | 4-aminoquina...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	2.62	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Epidermal growth factor receptor (Human)	BDBM31826 (CHEMBL188762 | BMC163482 Compound 3 | 4-aminoquina...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	0.100	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair