BDBM32026 6-quinolinamine::6-quinolylamine::BDBM32208::MLS000080747::SMR000036663::cid_11373::quinolin-6-amine

SMILES Nc1ccc2ncccc2c1

InChI Key InChIKey=RJSRSRITMWVIQT-UHFFFAOYSA-N

Data  1 KI  5 IC50  2 EC50

PDB links: 1 PDB ID matches this monomer.

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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 32026   

TargetNeutrophil cytosol factor 1(Homo sapiens)
University Of Copenhagen

Curated by ChEMBL
LigandPNGBDBM32026(6-quinolinamine | 6-quinolylamine | BDBM32208 | ML...)
Affinity DataKi: >2.00E+6nMAssay Description:Covalent inhibition of recombinant human His-tagged p47phox SH3A-B domain (151 to 285 residues) expressed in Escherichia coli BL21 (DE3) cells intera...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHeat shock protein HSP 90-alpha(Homo sapiens (Human))
Emory University

Curated by PubChem BioAssay
LigandPNGBDBM32026(6-quinolinamine | 6-quinolylamine | BDBM32208 | ML...)
Affinity DataIC50:  5.00E+4nMpH: 7.4 T: 2°CAssay Description:A fluorescence polarization based HTS assay has been developed and optimized for the identification of Hsp90 inhibitors by using tumor cell lysate Hs...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay
TargetMannose-6-phosphate isomerase(Homo sapiens (Human))
Burnham Center For Chemical Genomics

Curated by PubChem BioAssay
LigandPNGBDBM32026(6-quinolinamine | 6-quinolylamine | BDBM32208 | ML...)
Affinity DataIC50: >5.00E+4nMpH: 7.4 T: 2°CAssay Description:The purpose of this assay is to identify non-competititve inhibitors of human PMI. This is accomplished by using a G6PD- NADPH-coupled assay. In the ...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay
TargetProtein RecA(Mycobacterium tuberculosis H37Rv)
Broad Institute

Curated by PubChem BioAssay
LigandPNGBDBM32026(6-quinolinamine | 6-quinolylamine | BDBM32208 | ML...)
Affinity DataEC50:  5.95E+3nMAssay Description:Keywords: GFP-RecA intein, protein splicing, refolding, reducing reagent, GFP fluorescence Assay Overview: M. tuberculosis harbors three inteins, whi...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay
TargetGenome polyprotein(Hepatitis C virus genotype 1b (isolate BK) (HCV))
Biota Scientific Management

US Patent
LigandPNGBDBM32026(6-quinolinamine | 6-quinolylamine | BDBM32208 | ML...)
Affinity DataIC50:  100nMAssay Description:HCV polymerase inhibition assay: HCV polymerase reactions were carried out using a modified mothod of Howe et al., Antimicrobial Agents and Chemothe...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetGenome polyprotein(Hepatitis C virus genotype 3a (isolate NZL1) (HCV))
Biota Scientific Management

US Patent
LigandPNGBDBM32026(6-quinolinamine | 6-quinolylamine | BDBM32208 | ML...)
Affinity DataIC50:  30nMAssay Description:HCV polymerase inhibition assay: HCV polymerase reactions were carried out using a modified mothod of Howe et al., Antimicrobial Agents and Chemothe...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetHeat shock protein HSP 90-alpha(Homo sapiens (Human))
Emory University

Curated by PubChem BioAssay
LigandPNGBDBM32026(6-quinolinamine | 6-quinolylamine | BDBM32208 | ML...)
Affinity DataIC50:  3.81E+4nMpH: 7.4 T: 2°CAssay Description:A fluorescence polarization based HTS assay has been developed and optimized for the identification of Hsp90 inhibitors by using tumor cell lysate Hs...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay
TargetProtein RecA(Mycobacterium tuberculosis H37Rv)
Broad Institute

Curated by PubChem BioAssay
LigandPNGBDBM32026(6-quinolinamine | 6-quinolylamine | BDBM32208 | ML...)
Affinity DataEC50:  1.60E+4nMAssay Description:Keywords: GFP, refolding, reducing reagent, GFP fluorescence Assay Overview: M. tuberculosis harbors three inteins, which interrupt the DnaB, RecA, a...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay