BDBM320409 2-[[4-(trifluoromethyl)- phenoxy]methyl]-1H-pyrrolo- [3,2-b]pyridine-7-carboxylic acid::US10174026, Example 68::US9738637, Example 68

SMILES OC(=O)c1ccnc2cc(COc3ccc(cc3)C(F)(F)F)[nH]c12

InChI Key InChIKey=QPTYWJNUDAZOKY-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 320409   

TargetLysine-specific demethylase 5B(Human)
Celgene Quantical Research

US Patent
LigandPNGBDBM320409(US10174026, Example 68 | 2-[[4-(trifluoromethyl)- ...)
Affinity DataIC50: 100nMAssay Description:The ability of test compounds to inhibit the activity of Jarid1B was determined in 384-well plate format under the following reaction conditions: 0.8...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/1/2019
Entry Details
US Patent

TargetLysine-specific demethylase 5A(Human)
Celgene Quantical Research

US Patent
LigandPNGBDBM320409(US10174026, Example 68 | 2-[[4-(trifluoromethyl)- ...)
Affinity DataIC50: 100nMAssay Description:The enzymatic assay of Jarid1A activity is based upon Time Resolved-Fluorescence Resonance Energy Transfer (TR-FRET) detection. The ability of test c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/1/2019
Entry Details
US Patent

TargetLysine-specific demethylase 4C(Human)
Celgene Quantical Research

US Patent
LigandPNGBDBM320409(US10174026, Example 68 | 2-[[4-(trifluoromethyl)- ...)
Affinity DataIC50: 550nMAssay Description:The ability of test compounds to inhibit the activity of JMJD2C was determined in 384-well plate format under the following reaction conditions: 0.3 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/1/2019
Entry Details
US Patent