BDBM322116 N-Benzyl-1-(cyclohexylmethyl)-3-[(methyl]-1H-pyrazol-5-amine dihydrochloride::US10183913, Example 357

SMILES CN(Cc1cc(NC(=O)c2ccccc2)n(CC2CCCCC2)n1)C(=O)OC(C)(C)C

InChI Key InChIKey=WSDSDJPSUUWHFH-UHFFFAOYSA-N

Data  2 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 322116   

TargetSodium-dependent serotonin transporter(Human)
Sumitomo Dainippon Pharma

US Patent
LigandChemical structure of BindingDB Monomer ID 322116BDBM322116(US10183913, Example 357 | N-Benzyl-1-(cyclohexylme...)
Affinity DataKi:  10nMAssay Description:The [3H] citalopram binding was measured according to the method disclosed in Owens M. J. et al., J. Pharm. Exp. Ther., 283, 1305-1322 (1997). In spe...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/16/2019
Entry Details
US Patent

Target5-hydroxytryptamine receptor 2C(Human)
Sumitomo Dainippon Pharma

US Patent
LigandChemical structure of BindingDB Monomer ID 322116BDBM322116(US10183913, Example 357 | N-Benzyl-1-(cyclohexylme...)
Affinity DataKi:  74nMAssay Description:A solution of 200 μL in total was prepared by mixing 50 μL of [3H] mesulergine (manufactured by GE Healthcare) diluted with 50 mmol/L Tris-...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/16/2019
Entry Details
US Patent