BDBM322354 (R)-7-cyclopropyl-N-(2,2-dimethylquinuclidin-3-yl)benzo[b]thiophene-2-carboxamide::US10183938, Compound (R)-118
SMILES CC1(C)[C@H](NC(=O)c2cc3cccc(C4CC4)c3s2)C2CCN1CC2
InChI Key InChIKey=DMGKTIDNNWALJM-LJQANCHMSA-N
Data 2 KI
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 322354
TargetNeuronal acetylcholine receptor subunit alpha-7(Homo sapiens (Human))
Axovant Sciences
US Patent
Axovant Sciences
US Patent
Affinity DataKi: 140nMAssay Description:The ability of compounds to displace binding of radioactive ligands from human α7 nAChR was determined, as a measure of the affinity of the comp...More data for this Ligand-Target Pair
Affinity DataKi: 230nMAssay Description:[3H]BRL 43694 competition binding assay was performed under contract by Cerep Poitiers, France following the methods described in Hope, A. G et al., ...More data for this Ligand-Target Pair