BDBM322393 (R)-7-chloro-6-methyl-N-(1'-azaspiro[cyclopropane-1,2'-bicyclo[2.2.2]octan]-3'-yl)benzo[b]thiophene-2-carboxamide::US10183938, Compound (R)-156
SMILES Cc1ccc2cc(sc2c1Cl)C(=O)N[C@@H]1C2CCN(CC2)C11CC1
InChI Key InChIKey=CDBWVULDFPANMP-QGZVFWFLSA-N
Data 2 KI
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 322393
TargetNeuronal acetylcholine receptor subunit alpha-7(Homo sapiens (Human))
Axovant Sciences
US Patent
Axovant Sciences
US Patent
Affinity DataKi: 160nMAssay Description:The ability of compounds to displace binding of radioactive ligands from human α7 nAChR was determined, as a measure of the affinity of the comp...More data for this Ligand-Target Pair
Affinity DataKi: 300nMAssay Description:[3H]BRL 43694 competition binding assay was performed under contract by Cerep Poitiers, France following the methods described in Hope, A. G et al., ...More data for this Ligand-Target Pair