BDBM32304 6-(2,5-dimethoxyphenyl)benzo[d][2]benzazepine-5,7-dione::6-(2,5-dimethoxyphenyl)benzo[d][2]benzazepine-5,7-quinone::MLS000723361::SMR000236434::cid_2892892

SMILES COc1ccc(OC)c(c1)-n1c(=O)c2ccccc2c2ccccc2c1=O

InChI Key InChIKey=WJWLLHNCKPUFJY-UHFFFAOYSA-N

Data  6 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 32304   

TargetIsoform Bcl-X(L) of Bcl-2-like protein 1 (Bcl-xL)(Homo sapiens (Human))
Nmmlsc

Curated by PubChem BioAssay
LigandPNGBDBM32304(6-(2,5-dimethoxyphenyl)benzo[d][2]benzazepine-5,7-...)
Affinity DataEC50:  1.76E+4nMpH: 7.4 T: 2°CAssay Description:The HTS assay was conducted in 384-well microplates in a total assay volume per well of 10.1 microliters (5 microliters of bead mixture, 0.1 microlit...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay
TargetGlutathione S-transferase Mu 1(Homo sapiens (Human))
Nmmlsc

Curated by PubChem BioAssay
LigandPNGBDBM32304(6-(2,5-dimethoxyphenyl)benzo[d][2]benzazepine-5,7-...)
Affinity DataEC50:  2.98E+4nMAssay Description:University of New Mexico Assay Overview: Assay Support: NIH 1X01 MH079850-01 HTS to identify small molecule regulators of Bcl-2 family protein int...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay
TargetHeat shock factor protein 1(Mus musculus)
Broad Institute

Curated by PubChem BioAssay
LigandPNGBDBM32304(6-(2,5-dimethoxyphenyl)benzo[d][2]benzazepine-5,7-...)
Affinity DataEC50:  3.02E+4nMAssay Description:Keywords: Heat Shock Factor-1 (HSF-1), Stress Response, MG132, NIH3T3, Luminescence Assay Overview: Confirmation testing of small molecules identifie...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay
TargetBcl-2-like protein 2(Homo sapiens (Human))
Nmmlsc

Curated by PubChem BioAssay
LigandPNGBDBM32304(6-(2,5-dimethoxyphenyl)benzo[d][2]benzazepine-5,7-...)
Affinity DataEC50:  1.80E+4nMAssay Description:University of New Mexico Assay Overview: Assay Support: NIH 1X01 MH079850-01 HTS to identify small molecule regulators of Bcl-2 family protein int...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay
LigandPNGBDBM32304(6-(2,5-dimethoxyphenyl)benzo[d][2]benzazepine-5,7-...)
Affinity DataEC50:  1.67E+4nMAssay Description:University of New Mexico Assay Overview: Assay Support: NIH 1X01 MH079850-01 HTS to identify small molecule regulators of Bcl-2 family protein int...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay
TargetBcl-2-like protein 10 [11-204](Homo sapiens (Human))
Nmmlsc

Curated by PubChem BioAssay
LigandPNGBDBM32304(6-(2,5-dimethoxyphenyl)benzo[d][2]benzazepine-5,7-...)
Affinity DataEC50:  1.64E+4nMAssay Description:University of New Mexico Assay Overview: Assay Support: NIH 1X01 MH079850-01 HTS to identify small molecule regulators of Bcl-2 family protein int...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay