BDBM323660 (R)-2-(3-(2-ethoxy- phenoxy)piperidin-1-yl)- N-((5-oxo-2,5-dihydro- 1H-1,2,4-triazol-3- yl)methyl)pyrimidine-5- carboxamide::US10188653, Example 20.5::US9789110, 20.5

SMILES CCOc1ccccc1O[C@@H]1CCCN(C1)c1ncc(cn1)C(=O)NCc1nc(=O)[nH][nH]1

InChI Key InChIKey=SAKKZOMFXHMBRK-OAHLLOKOSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 323660   

TargetDiacylglycerol O-acyltransferase 2(Homo sapiens (Human))
Pfizer

US Patent
LigandPNGBDBM323660((R)-2-(3-(2-ethoxy- phenoxy)piperidin-1-yl)- N-((5...)
Affinity DataIC50:  68nMAssay Description:For determination of IC50 values, the reactions were carried out in 384-well white Polyplates (Perkin Elmer) in a total volume of 20 μL. To 14 o...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetDiacylglycerol O-acyltransferase 2(Homo sapiens (Human))
Pfizer

US Patent
LigandPNGBDBM323660((R)-2-(3-(2-ethoxy- phenoxy)piperidin-1-yl)- N-((5...)
Affinity DataIC50:  68nMAssay Description:For determination of IC50 values, the reactions were carried out in 384-well white Polyplates (Perkin Elmer) in a total volume of 20 μL. To 14 o...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent