BDBM325122 9-(4-(1-methyl-4-(trifluoromethyl)-1H-imidazol-2-::US10189841, Compound I-328::US10399980, Compound I-328

SMILES CN1CCN(c2ncccc2-c2ncc3[nH]c(=O)n(Cc4ccc(-c5nc(C(F)(F)F)cn5C)cc4)c3n2)CC1

InChI Key InChIKey=LYQXKDPHTPKLGK-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 325122   

TargetUbiquitin carboxyl-terminal hydrolase 1(Human)
Forma Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 325122BDBM325122(9-(4-(1-methyl-4-(trifluoromethyl)-1H-imidazol-2- ...)
Affinity DataIC50: 200nMAssay Description:The HTS assay was performed in a final volume of 20 μL in assay buffer containing 20 mM Tris-HCl (pH 8.0, (1M Tris-HCl, pH 8.0 solution; Corning...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/29/2019
Entry Details
US Patent

TargetUbiquitin carboxyl-terminal hydrolase 1(Human)
Forma Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 325122BDBM325122(9-(4-(1-methyl-4-(trifluoromethyl)-1H-imidazol-2- ...)
Affinity DataIC50: 1.10E+3nMAssay Description:The HTS assay was performed in a final volume of 20 μL in assay buffer containing 20 mM Tris-HCl (pH 8.0, (1M Tris-HCl, pH 8.0 solution; Corning...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2020
Entry Details
US Patent