BDBM326976 N-{4-[(3S)-2,3- dihydro[1,4]dioxino[2,3- b]pyridin-3- yl]benzyl}cyclopentanamine::US11957671, Compound 135::US9662339, 135

SMILES C(NC1CCCC1)c1ccc(cc1)[C@H]1COc2cccnc2O1

InChI Key InChIKey=KSADBAASPLWEFN-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 326976   

TargetLeukotriene A-4 hydrolase(Human)
Alkahest

US Patent
LigandPNGBDBM326976(N-{4-[(3S)-2,3- dihydro[1,4]dioxino[2,3- b]pyrid...)
Affinity DataIC50: 0.470nMAssay Description:The compounds of the invention are assessed for the ability to interact with human LTA4 hydrolase in an enzymatic assay that measures the ability of ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/3/2024
Entry Details
US Patent

TargetLeukotriene A-4 hydrolase(Human)
Alkahest

US Patent
LigandPNGBDBM326976(N-{4-[(3S)-2,3- dihydro[1,4]dioxino[2,3- b]pyrid...)
Affinity DataIC50: 0.470nMAssay Description:The compounds of the invention are assessed for the ability to interact with human LTA4 hydrolase in an enzymatic assay that measures the ability of ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/3/2019
Entry Details
US Patent