BDBM332061 US10189854, Compound 9::[1-[5-(2-Fluorophenyl)-pyrimidin-2-yl]-3,3-dimethyl-1,2-dihydro-indol-6-yl]-morpholin-4-yl-methanone

SMILES CC1(C)CN(c2cc(ccc12)C(=O)N1CCOCC1)c1ncc(cn1)-c1ccccc1F

InChI Key InChIKey=PXRTZIOIKVZBBJ-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 332061   

TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Human)
Gruenenthal

US Patent
LigandPNGBDBM332061(US10189854, Compound 9 | [1-[5-(2-Fluorophenyl)-py...)
Affinity DataIC50: 550nMAssay Description:The inhibiting effect of the compounds on the enzyme activity of human PDE4B1 was measured by the quantification of 5′-adenosine monophosphate ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/12/2019
Entry Details
US Patent