BDBM332121 1-[5-(2-Fluorophenyl)-pyrimidin-2-yl]-N-(3-methoxy-propyl)-spiro[1,2-dihydro-indole-3,1'-cyclopropane]-6-carboxylic acidamide::US10189854, Compound 75

SMILES COCCCNC(=O)c1ccc2c(c1)N(CC21CC1)c1ncc(cn1)-c1ccccc1F

InChI Key InChIKey=JRXDIVJSRDABJX-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 332121   

TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Human)
Gruenenthal

US Patent
LigandPNGBDBM332121(US10189854, Compound 75 | 1-[5-(2-Fluorophenyl)-py...)
Affinity DataIC50: 550nMAssay Description:The inhibiting effect of the compounds on the enzyme activity of human PDE4B1 was measured by the quantification of 5′-adenosine monophosphate ...More data for this Ligand-Target Pair
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Date in BDB:
6/12/2019
Entry Details
US Patent