BDBM332562 N-(2-Chloro-4- (trifluoromethyl)phenyl)-2-(6-(4- ((2- cyclopropylacetyl)glycyl)piperazin- 1-yl)-2-(3,6-dihydro-2H-pyran-4- yl)-5-ethyl-7-oxo- [1,2,4]triazolo[1,5-a]pyrimidin- 4(7H)-yl)acetamide::US20260015358, Example 275

SMILES CCc1c(N2CCN(C(=O)CNC(=O)CC3CC3)CC2)c(=O)n2nc(C3=CCOCC3)nc2n1CC(=O)Nc1ccc(C(F)(F)F)cc1Cl

InChI Key InChIKey=SUOKLTFZHZTSPD-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 332562   

TargetBifunctional 3'-5' exonuclease/ATP-dependent helicase WRN(Human)
Danatlas Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 332562BDBM332562(N-(2-Chloro-4- (trifluoromethyl)phenyl)-2-(6-(4- (...)
Affinity DataIC50: 100nMAssay Description:Source (MLPCN Center Name): The Scripps Research Institute Molecular Screening Center (SRISMC) Center Affiliation: The Scripps Research Institute, TS...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/29/2026
Entry Details
US Patent