BDBM337701 1-[3,5-Difluoro-4-(2-oxoimidazolidin-1-yl)phenyl]-3-[2-methyl-3-(trifluoromethyl)benzyl]-2,4-dioxo-1,2,3,4-tetrahydropyrimidine-5-carboxylic acid::US9751843, 75

SMILES Cc1c(Cn2c(=O)c(cn(-c3cc(F)c(N4CCNC4=O)c(F)c3)c2=O)C(O)=O)cccc1C(F)(F)F

InChI Key InChIKey=HWNZRPKBDZLXQX-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 337701   

TargetChymase(Homo sapiens (Human))
Bayer Pharma Aktiengesellschaft

US Patent
LigandPNGBDBM337701(1-[3,5-Difluoro-4-(2-oxoimidazolidin-1-yl)phenyl]-...)
Affinity DataIC50:  106nMAssay Description:The enzyme source used is recombinant human chymase (expressed in HEK293 cells) or chymase purified from hamsters' tongues. The substrate used fo...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent