BDBM34182 3-anilino-2H-isoquinolin-1-one::3-anilinoisocarbostyril::3-anilinoisoquinolin-1(2H)-one::3-phenylazanyl-2H-isoquinolin-1-one::MLS000043701::SMR000020713::cid_2142225

SMILES: O=c1[nH]c(Nc2ccccc2)cc2ccccc12

InChI Key: InChIKey=UZQIOQVHUUAJOZ-UHFFFAOYSA-N

Data: 29 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 29 hits for monomerid = 34182   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Procathepsin L (Human)	BDBM34182 (MLS000043701 | SMR000020713 | 3-anilinoisoquinolin...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>5.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Caspase-9 (Human)	BDBM34182 (MLS000043701 | SMR000020713 | 3-anilinoisoquinolin...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.72E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Apoptotic protease-activating factor 1 (Human)	BDBM34182 (MLS000043701 | SMR000020713 | 3-anilinoisoquinolin...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Apoptotic protease-activating factor 1 (Human)	BDBM34182 (MLS000043701 | SMR000020713 | 3-anilinoisoquinolin...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	3.31E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Phospholipase A2 (Human)	BDBM34182 (MLS000043701 | SMR000020713 | 3-anilinoisoquinolin...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>8.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Cysteine protease ATG4B (Human)	BDBM34182 (MLS000043701 | SMR000020713 | 3-anilinoisoquinolin...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	9.22E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Sentrin-specific protease 6 (Human)	BDBM34182 (MLS000043701 | SMR000020713 | 3-anilinoisoquinolin...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	345	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Sentrin-specific protease 8 (Human)	BDBM34182 (MLS000043701 | SMR000020713 | 3-anilinoisoquinolin...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>5.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Sentrin-specific protease 8 (Human)	BDBM34182 (MLS000043701 | SMR000020713 | 3-anilinoisoquinolin...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	899	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Caspase-3 (Human)	BDBM34182 (MLS000043701 | SMR000020713 | 3-anilinoisoquinolin...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.02E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Serine/threonine-protein phosphatase (Human)	BDBM34182 (MLS000043701 | SMR000020713 | 3-anilinoisoquinolin...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	3.16E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Serine/threonine-protein phosphatase PP1-alpha catalytic subunit (Human)	BDBM34182 (MLS000043701 | SMR000020713 | 3-anilinoisoquinolin...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	6.70E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Dual specificity protein phosphatase 6 (Rat)	BDBM34182 (MLS000043701 | SMR000020713 | 3-anilinoisoquinolin...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Glycoprotein 42 (HHV-4)	BDBM34182 (MLS000043701 | SMR000020713 | 3-anilinoisoquinolin...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.73E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Protein-tyrosine kinase 2-beta (Human)	BDBM34182 (MLS000043701 | SMR000020713 | 3-anilinoisoquinolin...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>6.95E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Bcl-2-related protein A1 (Mouse)	BDBM34182 (MLS000043701 | SMR000020713 | 3-anilinoisoquinolin...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	7.0	23
TBA									Citation and Details
					More data for this Ligand-Target Pair
Focal adhesion kinase 1 (Human)	BDBM34182 (MLS000043701 | SMR000020713 | 3-anilinoisoquinolin...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>7.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Mothers against decapentaplegic homolog 3 (Human)	BDBM34182 (MLS000043701 | SMR000020713 | 3-anilinoisoquinolin...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.96E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Dual specificity protein phosphatase 1 (Human)	BDBM34182 (MLS000043701 | SMR000020713 | 3-anilinoisoquinolin...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.07E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Dual specificity protein phosphatase 6 (Rat)	BDBM34182 (MLS000043701 | SMR000020713 | 3-anilinoisoquinolin...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.26E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
M-phase inducer phosphatase 2 (Human)	BDBM34182 (MLS000043701 | SMR000020713 | 3-anilinoisoquinolin...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>5.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
M-phase inducer phosphatase 2 (Human)	BDBM34182 (MLS000043701 | SMR000020713 | 3-anilinoisoquinolin...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>5.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
M-phase inducer phosphatase 2 (Human)	BDBM34182 (MLS000043701 | SMR000020713 | 3-anilinoisoquinolin...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>5.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
M-phase inducer phosphatase 2 (Human)	BDBM34182 (MLS000043701 | SMR000020713 | 3-anilinoisoquinolin...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	4.58E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
M-phase inducer phosphatase 2 (Human)	BDBM34182 (MLS000043701 | SMR000020713 | 3-anilinoisoquinolin...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	2.22E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
M-phase inducer phosphatase 2 (Human)	BDBM34182 (MLS000043701 | SMR000020713 | 3-anilinoisoquinolin...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	4.80E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Bcl-2-related protein A1 (Mouse)	BDBM34182 (MLS000043701 | SMR000020713 | 3-anilinoisoquinolin...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
M-phase inducer phosphatase 2 (Human)	BDBM34182 (MLS000043701 | SMR000020713 | 3-anilinoisoquinolin...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	3.28E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Cathepsin B (Human)	BDBM34182 (MLS000043701 | SMR000020713 | 3-anilinoisoquinolin...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.76E+4	n/a	n/a	n/a	n/a	6.8	23
TBA									Citation and Details
					More data for this Ligand-Target Pair