BDBM35022 benzothienopyrimidinone deriv., 14g

SMILES Cc1ccccc1-c1ccc2sc3c(=O)[nH]c(CN(C)C)nc3c2c1

InChI Key InChIKey=OTLXPFZNAMLUDF-UHFFFAOYSA-N

Data  2 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 35022   

TargetSerine/threonine-protein kinase pim-1(Human)
Abbott Laboratories

LigandChemical structure of BindingDB Monomer ID 35022BDBM35022(benzothienopyrimidinone deriv., 14g)
Affinity DataKi:  14nM ΔG°:  -10.7kcal/moleT: 2°CAssay Description:In 384-well v-bottom polypropylene plates, compound (2% DMSO) was mixed with Pim kinase and peptide substrate, followed by immediate initiation with ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/23/2009
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase pim-2(Human)
Abbott Laboratories

LigandChemical structure of BindingDB Monomer ID 35022BDBM35022(benzothienopyrimidinone deriv., 14g)
Affinity DataKi:  32nM ΔG°:  -10.2kcal/moleT: 2°CAssay Description:In 384-well v-bottom polypropylene plates, compound (2% DMSO) was mixed with Pim kinase and peptide substrate, followed by immediate initiation with ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/23/2009
Entry Details Article
PubMed