BDBM35040 benzothienopyrimidinone deriv., 17b

SMILES CN(C)Cc1nc2c3cc(ccc3sc2c(=O)[nH]1)N1CCCCC1

InChI Key InChIKey=MITSRVMYKFVRJP-UHFFFAOYSA-N

Data  2 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 35040   

TargetSerine/threonine-protein kinase pim-2(Human)
Abbott Laboratories

LigandPNGBDBM35040(benzothienopyrimidinone deriv., 17b)
Affinity DataKi:  120nM ΔG°:  -9.43kcal/moleT: 2°CAssay Description:In 384-well v-bottom polypropylene plates, compound (2% DMSO) was mixed with Pim kinase and peptide substrate, followed by immediate initiation with ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/23/2009
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase pim-1(Human)
Abbott Laboratories

LigandPNGBDBM35040(benzothienopyrimidinone deriv., 17b)
Affinity DataKi:  271nM ΔG°:  -8.95kcal/moleT: 2°CAssay Description:In 384-well v-bottom polypropylene plates, compound (2% DMSO) was mixed with Pim kinase and peptide substrate, followed by immediate initiation with ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/23/2009
Entry Details Article
PubMed