BDBM35525 3,3''''-methylenebis(4-hydroxy-coumarin::3,3''''-methylenebis(4-hydroxycoumarin)::3,3''''-methylenebis[4-hydroxycoumarin::4-hydroxy-3-((4-hydroxy-2-oxo-2H-chromen-3-yl)methyl)-2H-chromen-2-one::Bishydroxycoumarin::CHEMBL1466::DICUMAROL::US20250213569, Compound 23::dicoumarol::symmetric dicoumarol analogue, 1

SMILES: Oc1c(Cc2c(O)c3ccccc3oc2=O)c(=O)oc2ccccc12

InChI Key: InChIKey=DOBMPNYZJYQDGZ-UHFFFAOYSA-N

Data: 4 KI  13 IC50  3 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 20 hits for monomerid = 35525   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
NAD(P)H dehydrogenase [quinone] 1 (Human)	BDBM35525 (dicoumarol | 3,3''''-methylenebis(4-hydroxycoumari...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	2.60	n/a	n/a	n/a	n/a	7.5	n/a
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G-protein coupled receptor 35 (Human)	BDBM35525 (dicoumarol | 3,3''''-methylenebis(4-hydroxycoumari...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	9.78E+3	n/a	n/a	n/a	n/a
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G-protein coupled receptor 35 (Human)	BDBM35525 (dicoumarol | 3,3''''-methylenebis(4-hydroxycoumari...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	1.30E+3	n/a	n/a	n/a	n/a
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Enoyl-[acyl-carrier-protein] reductase [NADH] (Francisella tularensis subsp. tularensis (strain S...)	BDBM35525 (dicoumarol | 3,3''''-methylenebis(4-hydroxycoumari...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	4.70E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Urease (Jack bean)	BDBM35525 (dicoumarol | 3,3''''-methylenebis(4-hydroxycoumari...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.51E+4	n/a	n/a	n/a	n/a	n/a	n/a
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NAD(P)H dehydrogenase [quinone] 1 (Human)	BDBM35525 (dicoumarol | 3,3''''-methylenebis(4-hydroxycoumari...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	450	n/a	n/a	n/a	n/a	n/a	n/a
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Proprotein convertase subtilisin/kexin type 7 (Human)	BDBM35525 (dicoumarol | 3,3''''-methylenebis(4-hydroxycoumari...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.30E+3	n/a	n/a	n/a	n/a	n/a	n/a
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NAD(P)H dehydrogenase [quinone] 1 (Human)	BDBM35525 (dicoumarol | 3,3''''-methylenebis(4-hydroxycoumari...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	5	n/a	n/a	n/a	n/a	n/a	n/a
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NAD(P)H dehydrogenase [quinone] 1 (Human)	BDBM35525 (dicoumarol | 3,3''''-methylenebis(4-hydroxycoumari...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	450	n/a	n/a	n/a	n/a	n/a	n/a
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Integrase (Human immunodeficiency virus type 1)	BDBM35525 (dicoumarol | 3,3''''-methylenebis(4-hydroxycoumari...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
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Integrase (Human immunodeficiency virus type 1)	BDBM35525 (dicoumarol | 3,3''''-methylenebis(4-hydroxycoumari...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
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NAD(P)H dehydrogenase [quinone] 1 (Human)	BDBM35525 (dicoumarol | 3,3''''-methylenebis(4-hydroxycoumari...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	350	n/a	n/a	n/a	n/a	n/a	n/a
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G-protein coupled receptor 35 (Human)	BDBM35525 (dicoumarol | 3,3''''-methylenebis(4-hydroxycoumari...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	1.30E+3	n/a	n/a	n/a	n/a
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Bile salt export pump (Human)	BDBM35525 (dicoumarol | 3,3''''-methylenebis(4-hydroxycoumari...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	3.99E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Replicase polyprotein 1ab (2019-nCoV)	BDBM35525 (dicoumarol | 3,3''''-methylenebis(4-hydroxycoumari...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>5.00E+8	n/a	n/a	n/a	n/a	n/a	n/a
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NAD(P)H dehydrogenase [quinone] 1 (Human)	BDBM35525 (dicoumarol | 3,3''''-methylenebis(4-hydroxycoumari...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	404	n/a	n/a	n/a	n/a	7.5	25
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NAD(P)H dehydrogenase [quinone] 1 (Rat)	BDBM35525 (dicoumarol | 3,3''''-methylenebis(4-hydroxycoumari...) Show SMILES Show InChI	GoogleScholar	UniChem		1	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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G-protein coupled receptor 35 (Human)	BDBM35525 (dicoumarol | 3,3''''-methylenebis(4-hydroxycoumari...) Show SMILES Show InChI	GoogleScholar	UniChem		39	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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Cytochrome P450 2C9 (Human)	BDBM35525 (dicoumarol | 3,3''''-methylenebis(4-hydroxycoumari...) Show SMILES Show InChI	GoogleScholar	UniChem		600	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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Cytochrome P450 2C9 (Human)	BDBM35525 (dicoumarol | 3,3''''-methylenebis(4-hydroxycoumari...) Show SMILES Show InChI	GoogleScholar	UniChem		1.90E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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