BDBM356133 N-(4-(3-acetamidophenyl)-2- methylpyrimidin-5-yl)-2-fluoro- 5-(1-methyl-1H-pyrazol-3-yl)-4- (trifluoromethyl)benzamide::US9815846, Compound 133

SMILES CC(=O)Nc1cccc(c1)-c1nc(C)ncc1NC(=O)c1cc(-c2ccn(C)n2)c(cc1F)C(F)(F)F

InChI Key InChIKey=ZZOPPYJIDGZDPH-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 356133   

TargetHigh affinity nerve growth factor receptor(Homo sapiens (Human))
Merck Sharp & Dohme

US Patent
LigandPNGBDBM356133(N-(4-(3-acetamidophenyl)-2- methylpyrimidin-5-yl)-...)
Affinity DataIC50:  4.60nMAssay Description:TrkA functional activity was measured using a DiscoverX PathHunter assay. In this assay, U2OS cells express the human TrkA receptor as a fusion with ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent