BDBM356204 2-fluoro-N-(5-(oxazol-5- ylmethyl)-2-phenylpyridin-3-yl)- 5-(pyrimidin-2-yl)-4- (trifluoromethyl)benzamide::US9815846, Compound 204

SMILES Fc1cc(c(cc1C(=O)Nc1cc(Cc2cnco2)cnc1-c1ccccc1)-c1ncccn1)C(F)(F)F

InChI Key InChIKey=BKQHUSHYJFQTCY-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 356204   

TargetHigh affinity nerve growth factor receptor(Homo sapiens (Human))
Merck Sharp & Dohme

US Patent
LigandPNGBDBM356204(2-fluoro-N-(5-(oxazol-5- ylmethyl)-2-phenylpyridin...)
Affinity DataIC50:  8.30nMAssay Description:TrkA functional activity was measured using a DiscoverX PathHunter assay. In this assay, U2OS cells express the human TrkA receptor as a fusion with ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent