BDBM356652 US10213433, Compound 34::US11369599, Compound 34::US20240043404, Example 34::trans-4-(4-{[2-(4-chlorophenyl)-4,4-dimethylcyclohex-1-en-1-yl]methyl}piperazin-1-yl)-N-[(4-{[(4-methoxycyclohexyl)methyl]amino}-3-nitrophenyl)sulfonyl]-2-(1H-pyrrolo[2,3-b]pyridin-5-yloxy)benzamide

SMILES: CO[C@H]1CC[C@H](CNc2ccc(cc2[N+]([O-])=O)S(=O)(=O)NC(=O)c2ccc(cc2Oc2cnc3[nH]ccc3c2)N2CCN(CC3=C(CC(C)(C)CC3)c3ccc(Cl)cc3)CC2)CC1

InChI Key: InChIKey=CSBKUBOVPUXFLO-UHFFFAOYSA-N

Data: 9 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 9 hits for monomerid = 356652   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Apoptosis regulator Bcl-2 (Human)	BDBM356652 (trans-4-(4-{[2-(4-chlorophenyl)-4,4-dimethylcycloh...) Show SMILES Show InChI	GoogleScholar	UniChem		0.0100	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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Apoptosis regulator Bcl-2 (Human)	BDBM356652 (trans-4-(4-{[2-(4-chlorophenyl)-4,4-dimethylcycloh...) Show SMILES Show InChI	GoogleScholar	UniChem		0.0100	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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Apoptosis regulator Bcl-2 (Human)	BDBM356652 (trans-4-(4-{[2-(4-chlorophenyl)-4,4-dimethylcycloh...) Show SMILES Show InChI	GoogleScholar	UniChem		0.0100	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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Apoptosis regulator Bcl-2 (Human)	BDBM356652 (trans-4-(4-{[2-(4-chlorophenyl)-4,4-dimethylcycloh...) Show SMILES Show InChI	GoogleScholar	UniChem		<0.0100	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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Apoptosis regulator Bcl-2 (Human)	BDBM356652 (trans-4-(4-{[2-(4-chlorophenyl)-4,4-dimethylcycloh...) Show SMILES Show InChI	GoogleScholar	UniChem		<0.0100	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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Bcl-2-like protein 1 (Human)	BDBM356652 (trans-4-(4-{[2-(4-chlorophenyl)-4,4-dimethylcycloh...) Show SMILES Show InChI	GoogleScholar	UniChem		14	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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Bcl-2-like protein 1 (Human)	BDBM356652 (trans-4-(4-{[2-(4-chlorophenyl)-4,4-dimethylcycloh...) Show SMILES Show InChI	GoogleScholar	UniChem		14	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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Induced myeloid leukemia cell differentiation protein Mcl-1 (Human)	BDBM356652 (trans-4-(4-{[2-(4-chlorophenyl)-4,4-dimethylcycloh...) Show SMILES Show InChI	GoogleScholar	UniChem		>444	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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Bcl-2-like protein 2 (Human)	BDBM356652 (trans-4-(4-{[2-(4-chlorophenyl)-4,4-dimethylcycloh...) Show SMILES Show InChI	GoogleScholar	UniChem		852	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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