BDBM357663 7-(4-(tert- butyl)benzyl)- 3H-[1,2,31 triazolo[4,5- b]pyridin-5- amine::US10214527, Example 35

SMILES CC(C)(C)c1ccc(Cc2cc(N)nc3[nH]nnc23)cc1

InChI Key InChIKey=NMLMBCTZCQFFCW-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 357663   

TargetMyeloperoxidase(Human)
Bristol-Myers Squibb

US Patent
LigandPNGBDBM357663(US10214527, Example 35 | 7-(4-(tert- butyl)benzyl)...)
Affinity DataIC50: 500nMAssay Description:MPO peroxidation activity was measured in 100 mM KPi (pH 7.4) by utilizing the non-fluorescent reagent Amplex Red (Invitrogen catalog # A12222) which...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/20/2019
Entry Details
US Patent