BDBM357681 7-(3-(3,5- dimethyl-1H- pyrazol-1-yl) benzyl)-3H- [1,2,3]triazolo [4,5-b] pyridin- 5-amine::US10214527, Example 53

SMILES Cc1cc(C)n(n1)-c1cccc(Cc2cc(N)nc3[nH]nnc23)c1

InChI Key InChIKey=FEXSJWBDQNITDT-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 357681   

TargetMyeloperoxidase(Human)
Bristol-Myers Squibb

US Patent
LigandPNGBDBM357681(US10214527, Example 53 | 7-(3-(3,5- dimethyl-1H- p...)
Affinity DataIC50: 500nMAssay Description:MPO peroxidation activity was measured in 100 mM KPi (pH 7.4) by utilizing the non-fluorescent reagent Amplex Red (Invitrogen catalog # A12222) which...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/20/2019
Entry Details
US Patent