BDBM357722 N-((3-(2,6-difluoro-3,5-dimethoxyphenyl)-2-oxo-1-(pyridin-4-yl)-1,2,3,4-tetrahydropyrido[4,3-d]pyrimidin-7-yl)methyl)acrylamide::US10214528, Example 26::US10738048, Example 26::US11014923, Example 26::US11667635, Example 26::US9890156, Example 26

SMILES COc1cc(OC)c(F)c(N2Cc3cnc(CNC(=O)C=C)cc3N(C2=O)c2ccncc2)c1F

InChI Key InChIKey=ZHXRWVICIAWUOP-UHFFFAOYSA-N

Data  20 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 20 hits for monomerid = 357722   

TargetFibroblast growth factor receptor 1(Homo sapiens (Human))
Incyte

US Patent
LigandPNGBDBM357722(N-((3-(2,6-difluoro-3,5-dimethoxyphenyl)-2-oxo-1-(...)
Affinity DataIC50: >200nMAssay Description:TBDMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetFibroblast growth factor receptor 4(Homo sapiens (Human))
Incyte

US Patent
LigandPNGBDBM357722(N-((3-(2,6-difluoro-3,5-dimethoxyphenyl)-2-oxo-1-(...)
Affinity DataIC50:  20nMAssay Description:The inhibitor potency of the exemplified compounds was measured in an enzyme assay that measures peptide phosphorylation using FRET measurements to d...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetFibroblast growth factor receptor 3(Homo sapiens (Human))
Incyte

US Patent
LigandPNGBDBM357722(N-((3-(2,6-difluoro-3,5-dimethoxyphenyl)-2-oxo-1-(...)
Affinity DataIC50: >200nMAssay Description:TBDMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetFibroblast growth factor receptor 4(Homo sapiens (Human))
Incyte

US Patent
LigandPNGBDBM357722(N-((3-(2,6-difluoro-3,5-dimethoxyphenyl)-2-oxo-1-(...)
Affinity DataIC50:  20nMAssay Description:TBDMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetFibroblast growth factor receptor 1(Homo sapiens (Human))
Incyte

US Patent
LigandPNGBDBM357722(N-((3-(2,6-difluoro-3,5-dimethoxyphenyl)-2-oxo-1-(...)
Affinity DataIC50: >200nMAssay Description:The inhibitor potency of the exemplified compounds was measured in an enzyme assay that measures peptide phosphorylation using FRET measurements to d...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetFibroblast growth factor receptor 2(Homo sapiens (Human))
Incyte

US Patent
LigandPNGBDBM357722(N-((3-(2,6-difluoro-3,5-dimethoxyphenyl)-2-oxo-1-(...)
Affinity DataIC50: >200nMAssay Description:The inhibitor potency of the exemplified compounds was measured in an enzyme assay that measures peptide phosphorylation using FRET measurements to d...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetFibroblast growth factor receptor 3(Homo sapiens (Human))
Incyte

US Patent
LigandPNGBDBM357722(N-((3-(2,6-difluoro-3,5-dimethoxyphenyl)-2-oxo-1-(...)
Affinity DataIC50: >200nMAssay Description:The inhibitor potency of the exemplified compounds was measured in an enzyme assay that measures peptide phosphorylation using FRET measurements to d...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetFibroblast growth factor receptor 4(Homo sapiens (Human))
Incyte

US Patent
LigandPNGBDBM357722(N-((3-(2,6-difluoro-3,5-dimethoxyphenyl)-2-oxo-1-(...)
Affinity DataIC50:  20nMAssay Description:The inhibitor potency of the exemplified compounds was measured in an enzyme assay that measures peptide phosphorylation using FRET measurements to d...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetFibroblast growth factor receptor 1(Homo sapiens (Human))
Incyte

US Patent
LigandPNGBDBM357722(N-((3-(2,6-difluoro-3,5-dimethoxyphenyl)-2-oxo-1-(...)
Affinity DataIC50: >200nMAssay Description:The inhibitor potency of the exemplified compounds was measured in an enzyme assay that measures peptide phosphorylation using FRET measurements to d...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetFibroblast growth factor receptor 2(Homo sapiens (Human))
Incyte

US Patent
LigandPNGBDBM357722(N-((3-(2,6-difluoro-3,5-dimethoxyphenyl)-2-oxo-1-(...)
Affinity DataIC50: >200nMAssay Description:The inhibitor potency of the exemplified compounds was measured in an enzyme assay that measures peptide phosphorylation using FRET measurements to d...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetFibroblast growth factor receptor 3(Homo sapiens (Human))
Incyte

US Patent
LigandPNGBDBM357722(N-((3-(2,6-difluoro-3,5-dimethoxyphenyl)-2-oxo-1-(...)
Affinity DataIC50: >200nMAssay Description:The inhibitor potency of the exemplified compounds was measured in an enzyme assay that measures peptide phosphorylation using FRET measurements to d...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetFibroblast growth factor receptor 4(Homo sapiens (Human))
Incyte

US Patent
LigandPNGBDBM357722(N-((3-(2,6-difluoro-3,5-dimethoxyphenyl)-2-oxo-1-(...)
Affinity DataIC50:  20nMAssay Description:The inhibitor potency of the exemplified compounds was measured in an enzyme assay that measures peptide phosphorylation using FRET measurements to d...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetFibroblast growth factor receptor 1(Homo sapiens (Human))
Incyte

US Patent
LigandPNGBDBM357722(N-((3-(2,6-difluoro-3,5-dimethoxyphenyl)-2-oxo-1-(...)
Affinity DataIC50: >200nMAssay Description:The inhibitor potency of the exemplified compounds was measured in an enzyme assay that measures peptide phosphorylation using FRET measurements to d...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetFibroblast growth factor receptor 2(Homo sapiens (Human))
Incyte

US Patent
LigandPNGBDBM357722(N-((3-(2,6-difluoro-3,5-dimethoxyphenyl)-2-oxo-1-(...)
Affinity DataIC50: >200nMAssay Description:The inhibitor potency of the exemplified compounds was measured in an enzyme assay that measures peptide phosphorylation using FRET measurements to d...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetFibroblast growth factor receptor 3(Homo sapiens (Human))
Incyte

US Patent
LigandPNGBDBM357722(N-((3-(2,6-difluoro-3,5-dimethoxyphenyl)-2-oxo-1-(...)
Affinity DataIC50: >200nMAssay Description:The inhibitor potency of the exemplified compounds was measured in an enzyme assay that measures peptide phosphorylation using FRET measurements to d...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetFibroblast growth factor receptor 4(Homo sapiens (Human))
Incyte

US Patent
LigandPNGBDBM357722(N-((3-(2,6-difluoro-3,5-dimethoxyphenyl)-2-oxo-1-(...)
Affinity DataIC50:  20nMAssay Description:The inhibitor potency of the exemplified compounds was measured in an enzyme assay that measures peptide phosphorylation using FRET measurements to d...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetFibroblast growth factor receptor 1(Homo sapiens (Human))
Incyte

US Patent
LigandPNGBDBM357722(N-((3-(2,6-difluoro-3,5-dimethoxyphenyl)-2-oxo-1-(...)
Affinity DataIC50: >200nMAssay Description:The inhibitor potency of the exemplified compounds was measured in an enzyme assay that measures peptide phosphorylation using FRET measurements to d...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetFibroblast growth factor receptor 2(Homo sapiens (Human))
Incyte

US Patent
LigandPNGBDBM357722(N-((3-(2,6-difluoro-3,5-dimethoxyphenyl)-2-oxo-1-(...)
Affinity DataIC50: >200nMAssay Description:The inhibitor potency of the exemplified compounds was measured in an enzyme assay that measures peptide phosphorylation using FRET measurements to d...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetFibroblast growth factor receptor 3(Homo sapiens (Human))
Incyte

US Patent
LigandPNGBDBM357722(N-((3-(2,6-difluoro-3,5-dimethoxyphenyl)-2-oxo-1-(...)
Affinity DataIC50: >200nMAssay Description:The inhibitor potency of the exemplified compounds was measured in an enzyme assay that measures peptide phosphorylation using FRET measurements to d...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetFibroblast growth factor receptor 2(Homo sapiens (Human))
Incyte

US Patent
LigandPNGBDBM357722(N-((3-(2,6-difluoro-3,5-dimethoxyphenyl)-2-oxo-1-(...)
Affinity DataIC50: >200nMAssay Description:TBDMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent