BDBM361556 (S)-3-((1R,3R)- 1-(2- (difluoromethyl)- 6-fluoro-3- (2-((3- fluoropropyl) (methyl)amino) ethoxy)phenyl)- 3-methyl- 1,3,4,9- tetrahydro-2H- pyrido[3,4- b]indol-2-yl)- 2- methylpropanoic acid::US10221173, Example 148::US10590132, Example 148::US11046689, Example 148
SMILES C[C@@H](CN1[C@H](C)Cc2c([nH]c3ccccc23)[C@H]1c1c(F)ccc(OCCN(C)CCCF)c1C(F)F)C(O)=O
InChI Key
Data 4 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 4 hits for monomerid = 361556
Affinity DataIC50: 1.10nMAssay Description:The ability of compounds to bind to isolated Estrogen Receptor Alpha Ligand binding domain (ER alpha—LBD (GST)) was assessed in competition assays us...More data for this Ligand-Target Pair
Affinity DataIC50: 1.10nMAssay Description:The ability of compounds to bind to isolated Estrogen Receptor Alpha Ligand binding domain (ER alpha-LBD (GST)) was assessed in competition assays us...More data for this Ligand-Target Pair
Affinity DataIC50: 1.10nMAssay Description:ERα: The ability of compounds to bind to isolated Estrogen Receptor Alpha Ligand binding domain (ER alpha-LBD (GST)) was assessed in competition...More data for this Ligand-Target Pair
Affinity DataIC50: 0.420nMAssay Description:The ability of compounds to down-regulate Estrogen Receptor (ER) numbers was assessed in a cell based immuno-fluorescence assay using the MCF-7 human...More data for this Ligand-Target Pair