BDBM362386 N-(3-(7-(3,5-difluoro-2-methoxyphenyl)-5H-pyrrolo[2,3-b]pyrazin-2-yl)-phenyl)acrylamide ::US9834551, Example 43

SMILES: COc1c(F)cc(F)cc1-c1c[nH]c2ncc(nc12)-c1cccc(NC(=O)C=C)c1

InChI Key: InChIKey=KSYMHNOXAGUGBR-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 362386   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Tyrosine-protein kinase ITK/TSK (Human)	BDBM362386 (US9834551, Example 43 | N-(3-(7-(3,5-difluoro-2-me...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>100	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Tyrosine-protein kinase JAK3 (Human)	BDBM362386 (US9834551, Example 43 | N-(3-(7-(3,5-difluoro-2-me...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>100	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair