BDBM362412 N-(3-(3-methyl-1H-pyrrolo[2,3- b]pyridin-5- yl)phenyl)pyrrolidine-2- carboxamide::US9834551, Example 71

SMILES Cc1c[nH]c2ncc(-c3cccc(NC(=O)C4CCCN4)c3)cc12

InChI Key InChIKey=ZHENRIMLVUHDME-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 362412   

TargetTyrosine-protein kinase ITK/TSK(Human)
Arrien Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 362412BDBM362412(US9834551, Example 71 | N-(3-(3-methyl-1H-pyrrolo[...)
Affinity DataIC50: 100nMAssay Description:ITK and JAK3 Kinase assay procedures:Enzyme was incubated with substrate peptide in reaction buffer in the presence and absence of test compounds or ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/28/2019
Entry Details
US Patent

TargetTyrosine-protein kinase JAK3(Human)
Arrien Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 362412BDBM362412(US9834551, Example 71 | N-(3-(3-methyl-1H-pyrrolo[...)
Affinity DataIC50: 100nMAssay Description:ITK and JAK3 Kinase assay procedures:Enzyme was incubated with substrate peptide in reaction buffer in the presence and absence of test compounds or ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/28/2019
Entry Details
US Patent