BDBM384136 (4-methyl-1-(3-(3- (trifluoromethyl)- phenyl)-1H- pyrazolo[3,4- b]pyrazin-6-yl)- piperidin-4-yl)- methanamine::US10280171, Example 22::US10851110, Example 22::US11466017, Example 22

SMILES: CC1(CN)CCN(CC1)c1cnc2c(n[nH]c2n1)-c1cccc(c1)C(F)(F)F

InChI Key: InChIKey=VBWUNPVCLSZAAP-UHFFFAOYSA-N

Data: 4 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 384136   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Tyrosine-protein phosphatase non-receptor type 11 [E76K] (Human)	BDBM384136 (US10280171, Example 22 | (4-methyl-1-(3-(3- (trifl...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.75E+3	n/a	n/a	n/a	n/a	n/a	n/a
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Eukaryotic translation initiation factor 2-alpha kinase 3 (Human)	BDBM384136 (US10280171, Example 22 | (4-methyl-1-(3-(3- (trifl...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	976	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Tyrosine-protein phosphatase non-receptor type 11 [E76K] (Human)	BDBM384136 (US10280171, Example 22 | (4-methyl-1-(3-(3- (trifl...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.75E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Tyrosine-protein phosphatase non-receptor type 11 [E76K] (Human)	BDBM384136 (US10280171, Example 22 | (4-methyl-1-(3-(3- (trifl...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.75E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair