BDBM385997 (S)-6-(4-(4-fluorophenyl)-1-(1-hydroxybutan-2-yl)-1H- imidazol-5-yl)imidazo[1,2-b]pyridazine-3-carbonitrile::US10287295, Example 6'::US11352360, Example 6'

SMILES: CC[C@H](CO)n1cnc(c1-c1ccc2ncc(C#N)n2n1)-c1ccc(F)cc1

InChI Key: InChIKey=QYXUDJJTDANZPN-UHFFFAOYSA-N

Data: 4 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 385997   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
TGF-beta receptor type-1 [T204D] (Human)	BDBM385997 ((S)-6-(4-(4-fluorophenyl)-1-(1-hydroxybutan-2-yl)-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	5	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
TGF-beta receptor type-2 (Human)	BDBM385997 ((S)-6-(4-(4-fluorophenyl)-1-(1-hydroxybutan-2-yl)-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.02E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
TGF-beta receptor type-1 (Human)	BDBM385997 ((S)-6-(4-(4-fluorophenyl)-1-(1-hydroxybutan-2-yl)-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	5	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
TGF-beta receptor type-2 (Human)	BDBM385997 ((S)-6-(4-(4-fluorophenyl)-1-(1-hydroxybutan-2-yl)-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.02E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair