BDBM393298 N-(5-((2S,5R,6S)-5-amino-6- fluorooxepan-2-yl)-1-methyl- 1H-pyrazol-4-yl)-2-(2,6- difluoro-4-((S)-1- fluoroethyl)phenyl)thiazole-4- carboxamide::US9963446, Example 101

SMILES C[C@H](F)c1cc(F)c(-c2nc(cs2)C(=O)Nc2cnn(C)c2[C@@H]2CC[C@@H](N)[C@H](F)CO2)c(F)c1

InChI Key InChIKey=RZBVQRFWSKKEDZ-VCZPNBCRSA-N

Data  1 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 393298   

TargetSerine/threonine-protein kinase pim-1(Homo sapiens (Human))
Genentech

US Patent
LigandPNGBDBM393298(N-(5-((2S,5R,6S)-5-amino-6- fluorooxepan-2-yl)-1-m...)
Affinity DataKi:  0.00200nMAssay Description:Determination of the Pim kinase activity of a Formula I compound is possible by a number of direct and indirect detection methods. Certain exemplary ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent