BDBM393434 N-(5-((2S,5R,6R,7S)-5-amino-6- fluoro-7-methyloxepan-2-yl)-1- methyl-1H-pyrazol-4-yl)-2-(2,6- difluorophenyl)thiazole-4- carboxamide::US9963446, Example 121

SMILES C[C@@H]1O[C@@H](CC[C@@H](N)[C@H]1F)c1c(NC(=O)c2csc(n2)-c2c(F)cccc2F)cnn1C

InChI Key InChIKey=HKRXJKSQNXPSLH-NOISCPHCSA-N

Data  1 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 393434   

TargetSerine/threonine-protein kinase pim-1(Homo sapiens (Human))
Genentech

US Patent
LigandPNGBDBM393434(N-(5-((2S,5R,6R,7S)-5-amino-6- fluoro-7-methyloxep...)
Affinity DataKi:  0.00500nMAssay Description:Determination of the Pim kinase activity of a Formula I compound is possible by a number of direct and indirect detection methods. Certain exemplary ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent