BDBM398273 US10323018, Compound I-7

SMILES CCCc1nc(-c2ccc(Cl)cc2)nc2cc(C(=O)NCCCc3nnc[nH]3)ccc12

InChI Key InChIKey=MYSPRNOBSZLGNX-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 398273   

TargetNicotinamide phosphoribosyltransferase(Human)
Millennium Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 398273BDBM398273(US10323018, Compound I-7)
Affinity DataIC50: 30nMAssay Description:To measure the inhibition of NAMPT activity hNAMPT protein stock and anti 6His-Tb (Cisbio; Cat. No. 61HISTLB) is diluted to 3× final concentration wi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/10/2020
Entry Details
US Patent