BDBM40457 3-(4-chlorophenyl)-5-methyl-6-(phenylmethyl)-2-(trifluoromethyl)-1H-pyrazolo[1,5-a]pyrimidin-7-one::6-benzyl-3-(4-chlorophenyl)-5-methyl-2-(trifluoromethyl)-1H-pyrazolo[1,5-a]pyrimidin-7-one::CHEMBL522818::UNM000003620201::cid_2211071

SMILES Cc1nc2c(c([nH]n2c(=O)c1Cc1ccccc1)C(F)(F)F)-c1ccc(Cl)cc1

InChI Key InChIKey=NAEVADOJZKGAGC-UHFFFAOYSA-N

Data  2 KI  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 40457   

TargetfMet-Leu-Phe receptor(Homo sapiens (Human))
Nmmlsc

Curated by PubChem BioAssay
LigandPNGBDBM40457(3-(4-chlorophenyl)-5-methyl-6-(phenylmethyl)-2-(tr...)
Affinity DataKi:  2.50E+3nMAssay Description:University of New Mexico Assay Overview: Assay Support: NIH 1R03MH076381-01 Assay for Formylpeptide Receptor Family Ligands PI: Bruce S. Edwards, Ph...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay
TargetN-formyl peptide receptor 2(Homo sapiens (Human))
Nmmlsc

Curated by PubChem BioAssay
LigandPNGBDBM40457(3-(4-chlorophenyl)-5-methyl-6-(phenylmethyl)-2-(tr...)
Affinity DataKi: >4.03E+4nMAssay Description:University of New Mexico Assay Overview: Assay Support: NIH 1R03MH076381-01 Assay for Formylpeptide Receptor Family Ligands PI: Bruce S. Edwards, Ph...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay
TargetN-formyl peptide receptor 2(Homo sapiens (Human))
Nmmlsc

Curated by PubChem BioAssay
LigandPNGBDBM40457(3-(4-chlorophenyl)-5-methyl-6-(phenylmethyl)-2-(tr...)
Affinity DataIC50: >6.67E+4nMAssay Description:University of New Mexico Assay Overview: Assay Support: NIH 1R03MH076381-01 Assay for Formylpeptide Receptor Family Ligands PI: Bruce S. Edwards, Ph...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay
Target1-deoxy-D-xylulose-5-phosphate synthase(Mycobacterium tuberculosis)
University Of Illinois At Chicago

Curated by ChEMBL
LigandPNGBDBM40457(3-(4-chlorophenyl)-5-methyl-6-(phenylmethyl)-2-(tr...)
Affinity DataIC50: >2.00E+5nMAssay Description:Inhibition of Mycobacterium tuberculosis cloned 1-deoxy-D-xylulose-5-phosphate synthase expressed in Escherichia coliMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetfMet-Leu-Phe receptor(Homo sapiens (Human))
Nmmlsc

Curated by PubChem BioAssay
LigandPNGBDBM40457(3-(4-chlorophenyl)-5-methyl-6-(phenylmethyl)-2-(tr...)
Affinity DataIC50:  3.80E+3nMAssay Description:University of New Mexico Assay Overview: Assay Support: NIH 1R03MH076381-01 Assay for Formylpeptide Receptor Family Ligands PI: Bruce S. Edwards, Ph...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay