BDBM406760 3-fluoro-N-[2-(6-methoxypyridin-2-yl)-6-[4-(4-methylpiperazin-1-yl)butyl]pyrrolo[2,1-f][1,2,4]triazin-4-yl]pyridin-4-amine::US10336761, Example 43

SMILES: COc1cccc(n1)-c1nc(Nc2ccncc2F)c2cc(CCCCN3CCN(C)CC3)cn2n1

InChI Key: InChIKey=FNAZURMRPXJZOO-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 406760   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
TGF-beta receptor type-1 (Human)	BDBM406760 (3-fluoro-N-[2-(6-methoxypyridin-2-yl)-6-[4-(4-meth...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	2.20E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
TGF-beta receptor type-2 (Human)	BDBM406760 (3-fluoro-N-[2-(6-methoxypyridin-2-yl)-6-[4-(4-meth...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.50E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair