BDBM409130 1-(Azetidin-1-yl)-2-[3-fluoro-6-(4-fluoro-3-methyl-::US10377753, Example 69

SMILES Cc1cc(ccc1F)-c1cnc2c(F)cn(CC(=O)N3CCC3)c2c1

InChI Key InChIKey=HIPMQNZRIDKJFA-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 409130   

TargetGlutamate receptor ionotropic, NMDA 2B(Human)
Janssen Pharmaceutica

US Patent
LigandChemical structure of BindingDB Monomer ID 409130BDBM409130(1-(Azetidin-1-yl)-2-[3-fluoro-6-(4-fluoro-3-methyl...)
Affinity DataIC50: 25.1nMAssay Description:The assay depends on the binding of a tracer to the GluN2B subunit-containing NMDA receptors and the ability of the test compounds to displace such b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/6/2020
Entry Details
US Patent