BDBM410229 US10370388, Compound 61-A::US10370388, Compound 61-B

SMILES OC(=O)[C@@H]1CC(CN1C(=O)C(c1ccccc1)c1ccccc1)N1CCCC1Cc1ccccc1

InChI Key InChIKey=QBODAMCFFCQGDX-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 410229   

TargetType-2 angiotensin II receptor(Human)
Novartis

US Patent
LigandPNGBDBM410229(US10370388, Compound 61-B | US10370388, Compound 6...)
Affinity DataIC50: 83.3nMAssay Description: 120 μL membrane (5 mg protein/well) was incubated with 15 μL of [125I]-CGP42112A and 15 μL of compound at RT for 1.5 hrs. The binding...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/6/2020
Entry Details
US Patent

TargetType-2 angiotensin II receptor(Human)
Novartis

US Patent
LigandPNGBDBM410229(US10370388, Compound 61-B | US10370388, Compound 6...)
Affinity DataIC50: 107nMAssay Description: 120 μL membrane (5 mg protein/well) was incubated with 15 μL of [125I]-CGP42112A and 15 μL of compound at RT for 1.5 hrs. The binding...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/6/2020
Entry Details
US Patent