BDBM412782 N-(4-{[2-(5-fluoro-6-methylpyridin-2-yl)-7H-pyrrolo[2,3-d]pyrimidin-4-yl]amino}pyridin-2-yl)cyclopropanecarboxamide::US10399987, Example 47

SMILES: Cc1nc(ccc1F)-c1nc(Nc2ccnc(NC(=O)C3CC3)c2)c2cc[nH]c2n1

InChI Key: InChIKey=ZBPTYYFUGHUNMQ-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 412782   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
TGF-beta receptor type-1 [4-503,T204D] (Human)	BDBM412782 (US10399987, Example 47 | N-(4-{[2-(5-fluoro-6-meth...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.40	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
TGF-beta receptor type-2 (Human)	BDBM412782 (US10399987, Example 47 | N-(4-{[2-(5-fluoro-6-meth...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	26	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair